Inside the Ark
Valuable datasets and biospecimens can hold clues to questions not yet asked—and new technologies can reveal insights beyond a study’s original aims.
Eve’s Ark safeguards these resources and the knowledge needed to interpret them, preparing them for future discovery. Explore what we steward and what comes next.
[01] // Data and biospecimens
Our first research resources
We steward resources from three studies, including longitudinal reproductive-health records, genomic and microbiome data, and biospecimens held in our biobank. Together, they encompass more than one petabyte of data, study documentation, and the original researchers’ expertise.
Longitudinal records can reveal how health changes over time. Biospecimens can yield new measurements as methods advance. Their future use depends on scientific quality, context, and permitted uses.
Studies represented
Of research data
Participants represented
What the Ark holds
[01]
Longitudinal reproductive-health records
[02]
Genomic data
[03]
Microbiome data
[04]
Biospecimens
[05]
Study documentation
[06]
Original researchers’ knowledge
[02] // How the Ark began
Of research
Historical research investment
When a drug discovery company’s therapeutic programs were acquired, valuable data and biospecimens needed a lasting home. Representing more than a decade of work and $80 million in historical research investment, these resources held significant potential for future discovery.
The company’s board donated them to Eve’s Ark. Our team began recovering the data and the knowledge behind them: how the studies were conducted, what the records mean, and what future researchers need to understand. This work is shaping how we bring additional resources into the Ark.
[03] // Operating model
How the Ark works
[01]
We safeguard datasets and biospecimens with lasting scientific value, focusing on at-risk or orphaned resources. We preserve study documentation and original research teams’ knowledge so future researchers can build on that work.
[02]
We curate, document, and assess these resources for future research. Preparation may include de-identifying data, assessing biospecimen condition, linking samples with records, and harmonizing data across studies where appropriate.
[03]
We are developing a secure research environment where approved researchers can analyze data without taking copies of the underlying datasets. Scientific review, participant consent, contributor agreements, and permitted uses will guide access.
[04]
We are developing a model to reinvest value generated through research into lasting stewardship and further women’s health research. Recognition of participants, contributors, and original research teams remains central to this work.
[04] // TRE
The Trusted Research Enclave
Technology // Manifold
Cloud support // AWS
Our Trusted Research Enclave, or TRE, is a secure workspace under development with technology from Manifold and cloud support and services from AWS. Approved researchers will be able to analyze data within a governed environment, where access and use are controlled without distributing copies of the underlying datasets.
We are building tools to help researchers explore data using natural-language questions. Access will remain subject to permitted uses, scientific review, and the relevant agreements.
Biospecimens
Physical samples require separate scientific assessment and approval. Their use depends on condition, availability, and permitted uses. Access to data through the TRE does not authorize use of biospecimens.
[05] // Governance
Stewardship begins with trust
Behind every dataset and biospecimen are participants, researchers, and institutions whose contributions make discovery possible. Our governance foundations guide how we accept, care for, and enable responsible use of these resources.
We review participant consent, existing restrictions, and contributor agreements. Proposed research must align with permitted uses and receive the required approvals before access is granted.
We also document how data and biospecimens are prepared and changed over time, preserving the context future researchers need to interpret the evidence and recognize its contributors.
[06] // Progress
What we are doing now
Now
We are organizing and documenting our first datasets and biospecimens, preserving the original teams’ knowledge, and identifying where genomic sequencing or other laboratory analyses could generate new evidence. We are also developing the TRE and identifying our first research questions.
2027
Selected research pilots are planned for 2027. Access will open in stages as datasets, reviews, and agreements are ready.
Find your way into the Ark
Have a scientific question, data or biospecimens that need lasting care, or expertise to contribute? We’d like to hear from you.
